Types of Dermatomyositis

Dermatomyositis is classified into different subtypes based on the extent of skin or muscle involvement:

Adermatopathic dermatomyositis (Dermatomyositis sine dermatitis)

•  Muscle weakness and histopathological signs similar to dermatomyositis, without the cutaneous features3,5
•  Transient or poorly recognised rash2 
•  Many of these patients are likely misclassified and instead may be cases of overlap myositis5

Myopathic dermatomyositis

•  Characteristic skin rash together with muscle weakness1-3

Amyopathic dermatomyositis (Dermatomyositis sine myositis)

•  Cutaneous features without clinical muscle weakness for ≥ 6 months4
•  On biopsy, subclinical muscular involvement often detected2  
•  Accounts for 5–20% of patients with dermatomyositis4,5

Juvenile dermatomyositis occurs in patients < 18 years old at onset3

Gottron signs on hands (courtesy of Prof. Patrick Cherin)

Dermatomyositis affects both adults and children1, with subtypes varying in the extent of skin and muscle involvement.1-5

References

  1. Goyal NA. Continuum (MinneapMinn) 2019; 25:1564-85.
  2. Dalakas MC & Hohlfeld R. Lancet 2003; 362:971-82.
  3. Malik A et al. Front Neurol 2016; 7:64.
  4. Callander J et al. Br J Dermatol 2018; 179:1248-55.
  5. Schmidt J. J Neuromuscul Dis 2018; 5:109-29.

Science Hub

Sign up and connect to Science Hub to learn more about our recent ProDERM study and have access to symposia presentations, publications, posters and lectures.

Welcome to managedermatomyositis.com

This site is intented for EU Healthcare Professionals only.

Yes, I am a EU Healthcare Professional No, I am not a Healthcare Professional